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Literature summary extracted from

  • Baretton, G.; Luther, T.; Tjan-Heijnen, V.C.; Talieri, M.; Schmitt, M.; Sweep, F.C.; Span, P.N.; Magdolen, V.
    Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer (2006), Clin. Chem., 52, 1070-1079.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.117 diagnostics the enzyme might be a prognostic biomarker for breast cancer Homo sapiens
3.4.21.117 medicine expression of full-length KLK7 mRNA may represent a new prognostic marker in breast cancer disease Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.117 gene KLK7, overexpression in breast cancer cell lines aMCF-7, OVMZ-6, and MDA-231, quantitative expression analysis in wild-type native cells and in transfected cells, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.117 additional information Homo sapiens high enzyme activity shows a significantly better prognosis in breast cancer ?
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?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.117 Homo sapiens P49862
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3.4.21.117 Homo sapiens P49862 gene KLK7
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.117 breast cancer cell enzyme expression analysis in 155 patients, overview Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.117 additional information high enzyme activity shows a significantly better prognosis in breast cancer Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.117 kallikrein 7
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Homo sapiens
3.4.21.117 tissue kallikrein 7
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Homo sapiens